President Joe Biden is scheduled to participate in his first presidential news conference on Thursday, where he’s expected face a wide-ranging set of questions about the most pressing issues, including the federal response to the coronavirus pandemic, the state of the economy, immigration and gun control.

During the news conference, Biden is expected to highlight surpassing his initial goal of getting 100 million coronavirus vaccine doses in arms in his first 100 days in office. According to a White House official, he’ll also announce a new vaccine goal: 200 million doses in arms in his first 100 days, something his administration is already on pace to do.

The President is also expected to tout the passage of the $1.9 trillion American Rescue Plan — the sweeping coronavirus relief legislation that provided funding for schools, vaccinations and direct payments to millions of Americans.

The news conference, scheduled to take place at 1:15 p.m. ET on Thursday afternoon, comes more than two months after Inauguration Day — which is behind many of Biden’s presidential predecessors.

Along with victories on signing the relief into law and surpassing his vaccine goal, Biden has faced a number of mounting challenges since taking office.

His administration has faced scrutiny over the growing number of unaccompanied minors crossing the border and the limited press access to border facilities. And gun control advocates are pressing for reforms in the wake of two recent mass shootings. The President will also face questions over upcoming tax and spending plans, such as a reported $3 trillion jobs and infrastructure package.

Foreign policy will also take center stage as the President faces a slew of diplomatic hurdles with North Korea, Russia, China, Afghanistan and Myanmar.

For most of Biden’s formal events at the White House, he has spoken directly into a camera mounted with a teleprompter and read from a prepared speech. He regularly answers questions from reporters in an ad hoc fashion — following events at the White House or on the tarmac before boarding Air Force One, for example. But the Thursday afternoon question-and-answer session will be Biden’s most extended period of questioning since becoming president.

The President has been getting ready for days to face the White House press corps, according to multiple people. He has talked his strategy through with several members of his inner circle and even held an informal practice session earlier this week.

Aides have written sets of talking points for potential questions on a wide array of topics and Biden has taken home briefing books containing policy positions and framing for potential answers — something he has done before other major public appearances. His three-ring binders are typically organized by topic, with tabs separating the sections and the contents typed out in 14-point font. He has read them in the evenings and returned the next day with feedback for his team.

President Biden expected to announce new vaccination goal in first White House news conference